|Clonality:||Mouse Monoclonal Antibody|
|Molecular Weight:||42 kDa|
|Sensitivity:||WIF1 Mouse mAb detects endogenous levels of WIF1 protein.|
Purified recombinant fragment of human WIF1 expressed in E. coli.
|Storage:||Supplied in PBS, 0.005% sodium azide, PH 7.4. Store at -20°C. Stable for one year from the date of shipment.|
|Synonyms:||WIF antibody; WIF-1wnt inhibitory factor 1 antibody|
WIF1 (Wnt inhibitory factor 1) is a secreted protein that binds to Wnt proteins and inhibits their activity . It contains an N-terminal WIF domain and five EGF-like repeats . The WIF1 ortholog in Drosophila, Shifted, is required for Hedgehog stability and diffusion [3,4]. It has been reported that WIF1 expression is downregulated in many types of cancers [5-8].