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The 70 kDa ribosomal protein S6 kinase (p70 S6K) is a serine/threonine kinase. Two members of S6K family are named as S6K1 and S6K2, respectively. As the downstream target of PI3K/Akt/mTOR signaling pateway, S6K could be activated in response to many stimulus such as growth factors, cytokines and nutrients. [show the full text]
| Cat.No. | Product Name | Information | Publication | Customer Review |
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| S2843 | BI-D1870 | BI-D1870 is an ATP-competitive inhibitor of ribosomal S6 for RSK1, RSK2, RSK3 and RSK4 with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively. |
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| S1558 | AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and S6K with IC50 of 32 nM/17 n/47 nM and 85 nM, respectively. |
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| S1582 | H 89 2HCl | H 89 dihydrochloride is a protein kinase A inhibitor that also inhibits several other kinases with IC50 of 80, 120, 135, 270, 2600 and 2800 nM for S6K1, MSK1, PKA, ROCKII, PKBα and MAPKAP-K1b, respectively. |
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| S2163 | PF-4708671 | PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki of 20 nM and IC50 of 160 nM. |
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| S7064 | FMK | FMK is a potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1and RSK2. |
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