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PKC Inhibitors & Chemicals

Cat.No. Product Name Information Publication Customer Review
S1421 Staurosporine Staurosporine (AM-2282) is a potent PKC inhibitor with IC50 of 2.7 nM. (4)
S2248 CX-4945 (Silmitasertib) CX-4945 is a potent and selective inhibitor of CK2α and CK2α' with IC50 of 1 nM. (1)
S2791 Sotrastaurin (AEB071) Sotrastaurin (AEB071) is a potent selective pan-PKC inhibitor and highly inhibits PKCθ with Ki of 0.22 nM. (2)
S1055 Enzastaurin (LY317615) Enzastaurin (LY317615) is a potent PKC inhibitor for PKCβ, PKCα, PKCγ and PKCε with IC50 of 6 nM, 39 nM, 83 nM and 110 nM, respectively. (4)
S2911 Go 6983 Go 6983 is a pan PKC inhibitor against PKCα, PKCβ, PKCγ, PKCδ, PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.
S8064 Midostaurin (PKC412) Midostaurin (pkc412) is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.