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PLK Inhibitors

Cat.No. Product Name Information Publication Customer Review
S1109 BI 2536 BI 2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM. (14)
S2235 BI6727 (Volasertib) BI6727 (Volasertib) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM.
S1362 Rigosertib (ON-01910) Rigosertib (Estybon, Novonex, ON-01910) is a non-ATP-competitive inhibitor of PLK1 (Polo-like kinase 1) with IC50 of 9 nM. (1)
S2193 GSK461364 GSK461364 inhibits purified Plk1 with Ki of 2 nM. (1)
S1485 HMN-214 HMN-214 (IVX-214) is a potent inhibitor of Polo-like kinase (Plk)1 with IC50 of 118 nM.
S2898 MLN0905 MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM.
S1239 TAK-960 TAK-960 is a novel, potent and selective Plk1 inhibitor with IC50 of 8 nM.