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MAPK (mitogen-activated protein kinase) is a family of serine-threonine kinases that regulate multiple cellular functions such as mitogens, proinflammatory cytokines, gene expression and cell survival/apoptosis. ERK1/2, p38, ERK3/4, ERK5, ERK7/8, JNKs, and SAPKs have been identified in MAPK family. [show the full text]
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