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PDK1 (Phosphoinositide-dependent kinase-1) also known as PDPK1 (3-phosphoinositide dependent protein kinase-1) is a serine/threonine protein kinase, which functions as a master kinase to phosphorylate and activate a subgroup of the AGC family kinases such as PKB/Akt, PKC, S6K, SGK, and RSK, thus, playing a pivotal role in the PI3K/Akt signaling pathway. [show the full text]
| Cat.No. | Product Name | Information | Publication | Customer Review |
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| S1275 | BX-912 | BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. |
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| S1274 | BX-795 | BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively. |
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| S1106 | OSU-03012 | OSU-03012 is a potent inhibitor of recombinant PDK-1 with IC50 of 5 μM. |
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| S1556 | PHT-427 | PHT-427 is a dual Akt and PDPK1 inhibitor with Ki of 2.7 μM and 5.2 μM, respectively. |
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