| Cat.No. |
Product Name |
Information |
Publication |
Customer Review |
| S1172 |
JNJ 26854165 (Serdemetan) |
JNJ 26854165 (Serdemetan) is an orally bioavailable HDM2 antagonist.
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| S2678 |
NSC-207895 (XI-006) |
NSC-207895 suppresses MDMX with IC50 of 2.5 µM, leading to enhanced p53 stabilization/activation and DNA damage.
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| S2781 |
RITA (NSC 652287) |
RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells.
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| S2929 |
Pifithrin-α |
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes.
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| S8000 |
Tenovin-1 |
Tenovin-1 is a p53 activator and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2.
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