||Torin 2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM, and also exhibits potent cellular activity against ATM/ATR/DNA-PK with EC50 of 28 nM, 35 nM and 118 nM, respectively.
||Tyrphostin AG 879
||AG879 inhibits both ErbB2 and Flk-1 with IC50 of 1 μM.
||BYL719 strongly and selectively inhibits PI3Kα.
||Ciproxifan is a highly potent and selective H3-receptor antagonist with IC50 of 9.2 nM.
||INK 128 (MLN0128)
||INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM.
||Galeterone (TOK-001, VN/124-1) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively.
||MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM.
||Sirtinol is a specific SIRT1 and SIRT2 inhibtor with IC50 of 131 μM and 38 μM, respectively.
||GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively.
||Synephrine HCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.