||PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki of 20 nM and IC50 of 160 nM.
||NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs).
||Lithocholic acid is a bile acid that acts as a detergent to solubilize fats for absorption.
||Tyrphostin AG 1296
||Tyrphostin AG 1296 (AG 1296) is an inhibitor of PDGFR, FGFR and c-Kit with IC50 of < 1 μM, 12.3 μM and 1.8 μM, respectively.
||TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.
||AP26113 is a potent ALK inhibitor for ALK, FER, ROS/ROS1, FLT3 and FES/FPS with IC50 of 0.62 nM, 1.3 nM, 1.9 nM, 2.1 nM and 3.4 nM, respectively.
||GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM.
||ENMD-2076 L-(+)-Tartaric acid
||ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, a selective inhibitor of Aurora A and Aurora B with IC50 of 14 nM and 350 nM and also inhibits Flt3, Flt4 and VEGFR2 with IC50 of 1.86 nM, 15.9 nM and 58.2 nM, respectively.
||Vortioxetine (Lu AA21004) HBr
||Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
||GW0742 is a potent and highly selective PPARβ/δ agonist, binding to hPPARδ with IC50 of 1 nM.