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JNK is an important target which plays a crucial role in MAPK pathway, apoptosis and cell survival. JNK Regulates AP-1 Transcription Activity by phosphorylating c-Jun. Jnk, with p38 MAPK, belongs to MAPK pathway. Jnk is activated by MKK4 and MKK7.
| Cat.No. | Product Name | Information | Publication | Customer Review |
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| S1460 | SP600125 | SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM, respectively. |
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| S4901 | JNK-IN-8 | JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively. |
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