Home >> JAK/STAT >> JAK >>

JAK Inhibitors

Cat.No. Product Name Information Publication Customer Review
S5001 Tofacitinib citrate (CP-690550 citrate) Tofacitinib citrate (CP-690550) is a potent JAK3 inhibitor with IC50 of 1 nM. (5)
S2736 TG101348 (SAR302503) TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM.
S2789 Tofacitinib (CP-690550, Tasocitinib) CP-690550 is a novel inhibitor of JAK3 with IC50 of 1 nM. (11)
S2162 AZD1480 AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 1.3 nM and 0.26 nM, respectively. (1)
S1143 AG-490 AG-490 (Tyrphostin B42) is an inhibitor of EGFR, ErbB2 and JAK2 with IC50 of 0.1 μM, 13.5 μM, and ~10 μM, respectively. (2)
S2219 Cyt387 CYT387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 11 nM and 18 nM, respectively. (1)
S2686 NVP-BSK805 NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM.
S7144 BMS-911543
S8004 ZM 39923 HCl ZM39923 is an JAK inhibitor for JAK1, JAK3, EFGR and TGM2 with IC50 of 4.4 μM, 7.1 μM, 5.6 μM and 10 nM, respectively.
S2867 WHI-P154 WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM and also inhibits EGFR with IC50 of 4 nM.
S2851 Baricitinib (LY3009104, INCB28050) Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively.
S2796 WP1066 WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells .
S2902 S-Ruxolitinib S-Ruxolitinib is a JAK family inhibitor for JAK1 and JAK2 with IC50 of 3.3 nM and 2.8 nM, respectively.
S2692 TG101209 TG101209 is a potent inhibitor of JAK2, Flt3 and RET with IC50 of 6 nM, 25 nM and 17 nM, respectively.
S2806 CEP33779 CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM.
S2214 AZ 960 AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, respectively.
S2179 LY2784544 LY2784544 is selective to V617F mutant JAK2 with IC50 of 55 nM in Ba/F3 cells.
S1134 AT9283 AT9283 is a potent pan-Aurora inhibitor for Aurora A, Aurora B, JAK3, JAK2 and Abl with IC50 of 3 nM, 3 nM, 1.1 nM, 1.2 nM and 4 nM, respectively. (2)