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GSK-3 Inhibitors

Cat.No. Product Name Information Publication Customer Review
S2924 CHIR-99021 (CT99021) HCl CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. (5)
S1263 CHIR-99021 (CT99021) CHIR-99021 (CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. (5)
S2745 CHIR-98014 CHIR-98014 is a potent and selective GSK-3 inhibitor for GSK-3ɑ and GSK-3β with IC50 of 0.65 nM and 0.58 nM, respectively. (1)
S1075 SB 216763 SB 216763 is a potent and selective GSK-3α inhibitor with IC50 of 34.3 nM.
S2823 Tideglusib Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of GSK3 with IC50 of 60 nM.
S1590 TWS119 TWS119 is a GSK-3β inhibitor with IC50 of 30 nM.
S2729 SB 415286 SB 415286 is a potent GSK3α and GSK3β inhibitor with IC50 of 78 nM and ~78 nM, respectively.
S7063 LY2090314 LY2090314 is a potent GSK-3 inhibitor for GSK-3α and GSK-3β with IC50 of 1.5 nM and 0.9 nM, respectively.
S2926 TDZD-8 TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM.