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United States (Change Country)Cryptotanshinone Chemical Structure
Cryptotanshinone is a major tanshinone isolated from Salvia miltiorrhiza that exhibits multiple activities. It exhibits antitumor activity via inhibition STAT3 activity with an IC50 of 4.6 μM. It displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). It also improves cognitive impairment in Alzheimer’s disease transgenic mice by inhibition of acetylcholinesterase with an IC50 of 4.09 μM and reduction in Aβ peptide generation. [1][2]
[1] Neuroscience Letters 2009;452: 90–95
[2] Cancer Res 2009;69:193-202
| Molecular Weight (WM): | 296.36 |
|---|---|
| Formula: | C19H20O3 |
| Solubility(R.T.:25°C): | DMSO 12mg/mL |
| Water <1mg/mL | |
| Ethanol 10mg/mL |
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