Checkpoint activation | Chk Inhibitor Review

Research Area

Cat.No.	Product Name	Information	Publication	Customer Review
S1532	AZD7762	AZD7762 is a novel CHK1 and CHK2 inhibitor with IC50 of 5 nM and <10 nM, respectively.	(6)	(2)
S2626	LY2603618 (IC-83)	LY2603618 (IC-83) is a selective Chk1 inhibitor with potential anti-tumor activity.
S2683	CHIR-124	CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM.
S2735	SCH 900776	SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM and also inhibits CDK2 with IC50 of 160 nM.
S2904	PF 477736	PF 477736 is a ChK inhibitor against ChK1, ChK2, VEGFR2, Yes and Fms with IC50 of 0.49 nM, 47 nM, 8 nM, 14 nM and 10 nM, respectively.