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CCR5 is a cell surface beta chemokine receptor. HIV uses CCR5 or CXCR4 as a coreceptor to enter its host cell by binding to a CD4 receptor.Deletion mutation of CCR5 is resistant to HIV-1 infection. Inhibiting human immunodeficiency virus type 1 (HIV-1) infection by blocking the host cell coreceptors CCR5 and CXCR4 is an emerging strategy for antiretroviral therapy.
| Cat.No. | Product Name | Information | Publication | Customer Review |
|---|---|---|---|---|
| S2004 | Vicriviroc Malate | Vicriviroc (SCH-417690, SCH-D) is a potent CCR5 antagonist with IC50 of 0.91 nM. |
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