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Caspase

Caspases are the family of cysteine aspartate-specific proteases that play a critical role in proteolytic execution, with significant roles in apoptosis, necrosis, cytokine maturation, inflammatory responses, cellular differentiation, and development.  [show the full text]

Inhibitors

Cat.No. Product Name Information Publication Customer Review
S2738 PAC-1 PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM.
S2927 Apoptosis Activator 2 Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.
S7015 Birinapant (TL32711) Birinapant (TL32711) is a SMAC mimetic and inhibitor of IAP family proteins.
S7023 Z-VAD-FMK

Caspase

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