| Cat.No. |
Product Name |
Information |
Publication |
Customer Review |
| S1006 |
Saracatinib (AZD0530) |
Saracatinib (AZD0530) is a Src inhibitor for c-Src and v-Abl with IC50 of 2.7 nM and 30 nM, respectively.
|
 (9)
|
 (1)
|
| S1107 |
Danusertib (PHA-739358) |
Danusertib (PHA-739358) is an Aurora inhibitor for Aurora A/B/C, Bcr-Abl, c-RET and FGFR with IC50 of 13 nM/79 nM/61 nM, 25 nM, 31 nM and 47 nM, respectively.
|
(2)
|
(2)
|
| S1134 |
AT9283 |
AT9283 is a potent pan-Aurora inhibitor for Aurora A, Aurora B, JAK3, JAK2 and Abl with IC50 of 3 nM, 3 nM, 1.1 nM, 1.2 nM and 4 nM, respectively.
|
(2)
|
(1)
|
| S2158 |
KW 2449 |
KW-2449 potently inhibits Flt3, Abl and Aurora A with IC50 of 6.6 nM, 14 nM and 48 nM, respectively.
|
|
(1)
|
| S2243 |
WP1130 |
WP1130 (degrasyn) is a selective deubiquitinase (DUB) inhibitor and also inhibits Bcr/Abl with IC50 of 1.8 μM.
|
(3)
|
|
| S1369 |
Bafetinib (INNO-406) |
Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM and 19 nM, respectively.
|
|
|
| S2202 |
NVP-BHG712 |
NVP-BHG712 is a specific inhibitor of c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM and also inhibits EphB4 and VEGFR2 with ED50 of 25 nM and 4.2 μM, respectively.
|
|
|
| S2899 |
GNF-2 |
GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, inhibiting the proliferation of the Bcr-Abl-expressing cells with IC50 of 138 nM.
|
|
|
| S2634 |
DCC-2036 (Rebastinib) |
DCC-2036 is a conformational control inhibitor of Abl1 and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, respectively.
|
|
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