| Cat.No. |
Product Name |
Information |
Publication |
Customer Review |
| S1001 |
ABT-263 (Navitoclax) |
ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.
|
 (15)
|
 (10)
|
| S1002 |
ABT-737 |
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively.
|
(39)
|
(8)
|
| S1057 |
Obatoclax mesylate (GX15-070) |
Obatoclax (GX15-070) is an inhibitor of Bcl-2 with Ki of 0.22 μM.
|
(8)
|
(3)
|
| S1121 |
TW-37 |
TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.
|
(4)
|
(2)
|
| S2812 |
AT101 |
AT-101 is a BH3 mimetic known to be a potent inhibitor of antiapoptotic Bcl-2 family members.
|
|
|
| S1071 |
HA14-1 |
HA14-1 is a nonpeptidic ligand of a Bcl-2 surface pocket with IC50 of~9 μM.
|
|
|
| S7034 |
BM-1074 |
BM-1074 is a potent and efficacious Bcl-2/Bcl-xL inhibitor with Ki of <1 nM.
|
|
|
| S8048 |
ABT-199 |
ABT-199 is a Bcl-2-selective inhibitor with Ki < 0.010 nM.
|
|
|
