| Cat.No. |
Product Name |
Information |
Publication |
Customer Review |
| S1009 |
BEZ235 (NVP-BEZ235) |
BEZ235 (NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively, and also inhibits ATR with IC50 of 21 nM.
|
 (25)
|
 (7)
|
| S1092 |
KU-55933 |
KU-55933 is a potent and specific ATM inhibitor with IC50 and Ki of 13 nM and 2.2 nM, respectively.
|
(11)
|
(1)
|
| S2758 |
Wortmannin |
Wortmannin is a multi-target inhibitor of MLCK and PI3K with IC50 of 170 nM and 3 nM, respectively.
|
(1)
|
|
| S1570 |
KU-60019 |
KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.
|
(1)
|
|
| S8007 |
VE-821 |
VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively.
|
|
|
| S2245 |
CP-466722 |
CP-466722 is an potent and reversible ATM inhibitor.
|
(2)
|
|
| S2817 |
Torin 2 |
Torin 2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM, and also exhibits potent cellular activity against ATM/ATR/DNA-PK with EC50 of 28 nM, 35 nM and 118 nM, respectively.
|
|
|
