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AMPK

AMPK (AMP-activated protein kinase) plays a pivotal role in the regulation of cellular energy homeostasis as the principal energy sensor in most eukaryotic cells. In response to stress, AMPK activation switches on catabolic pathways that generate ATP while simultaneously inactivating biosynthetic pathways that consume ATP.  [show the full text]

Inhibitors

Cat.No. Product Name Information Publication Customer Review
S2697 A-769662 A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM and inhibits fatty acid synthesis with IC50 of 3.2 μM.
S1802 Acadesine Acadesine results in accumulation of ZMP, which mimics both activating effects of AMP on AMPK and AMPKK.

AMPK

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