Home >> Neuronal Signaling >> 5-HT Receptor >>

5-HT Receptor Antagonists & Agonists

Cat.No. Product Name Information Publication Customer Review
S2698 RS-127445 RS-127445 is a selective 5-HT2B antagonist with pKi of 9.5 and pIC50 of 10.4.
S2691 BMY 7378 BMY 7378 is a multiple inhibitors of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively.
S2663 WAY-100635 HCl WAY 100635 is a potent and selective 5-HT agonist with IC50 of 0.95 nM.
S2677 BRL-15572 BRL-15572 is a 5-HT1D antagonist with pKi of 7.9.
S2849 SB-269970 HCl SB-269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3.
S2875 Prucalopride Prucalopride is a selective, high affinity 5-HT receptor agonistfor 5-HT4a and 5-HT4b with Ki of 2.5 nM and 8 nM, respectively.
S2894 SB-742457 SB-742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63.
S8021 Vortioxetine (Lu AA21004) hydrobromide Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
S8010 PRX-08066 PRX-08066 is a selective 5-HT2B antagonist with IC50 of 3.4 nM.
S2865 VUF 10166 VUF10166 is a novel, potent and competitive antagonist to 5-HT3A with Ki of 0.04 nM.
S2856 SB 271046 SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.
S2852 BRL 54443 BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively.
S2669 LY310762 LY310762 is a 5-HT1D antagonist with Ki of ~0.2 μM.
S2860 IEM 1754 Dihydrobromide IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.